How to Achieve Effective
Headache Pain Relief

General Application Procedure for Headaches
Our Topical Solution headache relief products PenQuell™ and CorProfen™ are applied topically to the temporal (temples) area of your head FIRST and then if necessary moving to the other areas of your body beginning at the head and working your way down your body by applying the topical solution to the areas on your body as dipicted on the above diagram beginning with your head as indicated by the RED DOTS.
Any successful treatment for headaches involves reaching the source of a headache by attacking the inflammed and/or agitated nerves to cause the nerves to relax and thereby allowing blood and oxygen to flow once again into the affected area to in essery ts on this web site will cause the irritated nerves to relax and as a result, as described, dramatically reduce the severity of your headache.
Always begin with the temples first, then proceed to the other areas of you body as indicated on the application diagram.
• Gently rub the applicator ont the spot as indicated by the RED DOT, starting with the temples on both sides of your head.
• Gently apply 2 to 3 very light coats of the solution in a continuous circular motion.
• The area you cover with the solution should be at least as large as a nickel.
• The solution will remain moist for a few minutes.
• Remain in a relaxed position to shorten the time frame for headache relief.
• Most people will feel headache relief in as little as 5 - 10 minutes.
• Additional applications may be necessary to achieve a desirable level of headache pain relief, a migraine for instance may take up to three applications 10 minutes apart.
• Experiment with the other locations on your body to find the right combination of applications to maximize your headache relief.

Headache Pain Relief
Causes for Headaches
All pain results when nerve fibers are damaged...ALL PAIN. Damaged fibers aren't able to send messages from the affected area causing your headache to your brain as they normally do. Instead the messages become confused and exaggerated, causing chronic, often excruciating pain that may persist
for hours and even days.
Recurring headaches are difficult to treat even by even the best of physicians and specialists. Specific treatment of headache problems can be recommended by a physician, preferably a specialist – preferably one who deals with neural and chronic pain conditions. How a doctor deals with your unique headache symptoms will depend on...
• Your age, overall health, and medical history
• Extent, severity, and time sensitive elements of your headache.
• Your tolerance for specific medications, procedures, or therapies
• Diagnosis of the possible causes of your headache
• Your opinion or preference for the recommended treatment for your headaches

What Causes Headaches?
Scientists HAVE YET to completely unravel the cause or causes of headaches. It was once believed that constriction and dilation of blood vessels caused migraine headache, while muscle contraction caused tension headache. The constriction of vessels in the head was thought to cause the aura of migraine, as well as the nausea and vomiting. The subsequent relaxing, or dilation, of the vessels then brought on the pounding pain associated with migraine.
These changes are still thought to play a big role in headache pain, but a much more complicated explanation is beginning to emerge from recent scientific findings. Many experts now speculate that migraine and tension headache have the SAME ORIGINS IN THE BRAIN.
The Body's “Anti-Pain” System
The brain stem—the structures of the brain located behind the eyes and nose—contains an “anti-pain” system. When this area recognizes an incoming nerve signal as painful, it responds with a powerful pain-relieving effect.
The pain from a headache is thought to begin with the trigeminal nerve, which is located in the brain stem. The largest in the head, this nerve carries sensory impulses to and from the face. When stimulated, perhaps by a certain headache trigger, it releases a burst of neurotransmitters (chemicals that pass impulses from one nerve to the next). This, in turn, normally prompts release of yet another neurotransmitter called serotonin.
Serotonin acts as a filter, screening out unimportant signals—for example, weak, repetitive, or familiar background noise like music and other people's conversations—while admiting signals that demand attention, such as unusual or significant sounds like a baby's cry or your name being called. The more serotonin, the greater the screening action. High serotonin levels correlate with sleep.
Under ordinary circumstances, pain signals from the trigeminal nerve are counteracted by increased serotonin levels. But in people suffering a headache, serotonin levels often prove too low. Scientific tests have shown a clear relationship. When injected with a drug that depletes serotonin, test subjects got headaches. Likewise, when they were injected with serotonin, the headache went away.
Significantly, lack of serotonin has also been implicated in depression and sleep disorders, two problems that afflict many headache sufferers. The role of serotonin is not, by itself, a full explanation of headache. But as researchers continue to unlock the secrets of our neurotransmmitters and their effect on pain, mood, and other body functions, we can look forward to an ever better understanding of the causes—and cures—of headache.

Self-Care for Headaches
After talking with your doctor, the use of the following over-the-counter medications may ease your Headache pain:
1. PenQuell™...Field application trials with people who suffer from headaches has proven that this product is highly effective dramatically reducing excrutiating Headaches. PenQuell is applied topically to RED DOTS as indicated starting with the head to get right to the source of the headache by not attacking the inflammation of the nerves but in affect causing the nerves to relax and in essence "turn off the pain signal to your spinal chord, the pain connector to your brain". This product will not cause a burning sensation nor will it irritate your skin.
ZERO side effects exist with our PenQuell™ product no matter how many applications are applied to your temples or any other areas as your body. How long an application will deliver headache relief depends on your personal physiology as an individual and the severity of your headache but in general up to four to eight hours of headache relief can be expected.<./p>
Begin by applying our PenQuell™ topical solution to the center of your temple about the size of a nickel, LET IT DRY and then apply a heat compress or pad over the treatment area if you so desire.
2. Corprofen™... was developed to provide an effective topical alternative treatment to oral or injected pain medications. During pre-clinical asessments of Corprofen™, many patients who used Corprofen™ for pain management required lower doses of oral medications. CorProfen was given in two physical therapy clinics by therapists who had no knowledge or connection between the development of the product and its use. These patients were asked to use the product and review its efficacy in six different clinical settings.
A key difference between PenQuell™ and Corprofen™ and other topical pain-relieving preparations is Corprofen™ contains a combination of topical analgesic pain medication, an anti-inflammatory medication and a proprietary transdermal carrier which allows penetration below the skin.
3. Capsaicin (not on our site) – This cream, made from the seeds of hot chili peppers, may relieve skin hypersensitivity. It's the only medication approved by the FDA ftreatment of arthritis. Capsaicin (Capzasin-P, Zostrix) depletes your nerve cells of a chemical called substance P, which is involved in sending pain messages to your brain. You periodically rub the cream on your temples, usually three times a day. Capsaicin can cause a burning sensation and irritate your skin, but these side effects usually disappear over time. Follow the application instructions carefully because
Capsaicin cream can be very irritating if rubbed on or in nonaffected parts of your body, such as your eyes.
4. Topical Analgesics and Anesthetics – Aspirin mixed into an absorbing cream or nonprescription-strength lidocaine cream may reduce skin hypersensitivity. Use extreme caution when applying any cream that contains lidocaine to your face. We offer lidocaine cream on our site at http://www.painreliefforpain.com
Remember that the two Topical Solutions on this web site are applied topically to the RED DOTS as indicated and are formulated to get right to the source of your headache by not attacking the inflammation of the the nerve but rather causing the nerve to relax and in essence "turning off the pain signal to your spinal chord, the pain connector to your brain". Topical Solutions are not a cure, however, our products will bring you considerable, non-habit forming, non-addictive, non-corrosive, headache pain relief.


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